Structural Biology of Bacterial Secretion Systems and Effectors

Structural Biology of Bacterial Secretion Systems and Effectors

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17 Mar 2025

February 17-20. The lab was out at the International T4SS conference in Nancy, France.

Chloé presented here data on the VirJ protein. 

laurent presented a new story on a protein involved in conjugation. 

Alpay and Priscillia  had posters on H. pylori T4SS. 

Lot of work  but great experience

17 Mar 2025

Conference BMSV, CapeTown 2025, february 2-7

Sibylle and Laurent had the chance to participate to the 2025 BMSV conference in Cape Town, South Africa. 

A spectacular venue and Scientific program !

17 Mar 2025

January 2025 we have a new comer !

Chaimaa Chouaib start her Master 2 internship in the lab. She will stay with us 6 months and try to solve the structure of bacterial effectors.

Welcome Chaimaa and good luck !

20 Dec 2024

2024 Christmas lunch at the Altitude restaurant !

29 Nov 2023

New article from the team

We publish a book chapter describing a pipeline from protein to structure determination and analysis using X-ray crystallography in the beautiful book Methods in Molecular Biology edited by E. Cascales and L. Journet.

Congratulations Chloé  !

Check out the article (Dugelay et al., 2023) here !

13 Nov 2023

BSI conference 2023

We are at the BSI 2023 conference organised in Marseille. Chloé is presenting her poster on her results on Brucella and Laurent is giving a talk on Helicobacter latest developpement

10 Nov 2023
Chloé and Marine carving !

Chloé and Marine carving !

IBCP Pumpkin carving contest Winner

The lab has participated to the IBCP carving contest.

and won the prize ! for the second year

Back to back champion ! well done

10 Nov 2023

The winning photo showing the scene created with the two pumpkins

2 Oct 2023

Alpay Aydin starts his PhD on Helicobacter pylori type IV secretion system. He will be co-supervised by Laurent and Priscillia

Welcome Alpay !

3 Sep 2023

EMBO Workshop Istanbul

Laurent is giving a lecture at the EMBO workshop on Macromolecular Complexes. Great venue and wonderful hospitality

29 Nov 2023
Crystal structure of the CagI/K2 complex (Blanc et al., 2023)

Crystal structure of the CagI/K2 complex (Blanc et al., 2023)

New article from the team

Our paper on the structure and function of CagI is published in PloS Pathogens. Congratulations to Marine for her great work and big thanks to our wonderful collaborators.

 Check out the paper Blanc et al. 2023  here !

6 Jan 2023
NyxB dimer crystal structure (Louche et al., 2023)

NyxB dimer crystal structure (Louche et al., 2023)

New article from the team

In a study led by Suzana Salcedo, we publish the identification and structure of a novel family of Brucella effectors : the Nyx family in Nature Communications (Louche et al., 2023)

Congratulations to Arthur Louche and Amandine Blanco !

If you want to know more about this work look here

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