Structural Biology of Bacterial Secretion Systems and Effectors

Structural Biology of Bacterial Secretion Systems and Effectors

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26 Nov 2025

Chloé's PhD defense ! A new doctor in the team

Chloé Dugelay has defended brilliantly her PhD in front of a large audience and with an extraordinary Jury:

Rémi Fronzes, Laure Journet, Romé Voulhoux, Suzana Salcedo and Patricia Doublet. 


Congratulations Chloé and all the best for the future

26 Nov 2025
VirJD1 crystal structure

VirJD1 crystal structure

New article from the team !

We publish the crystal structure of VirJ domain 1 in Acta Cryst. F at a resolution of 1.7 Å. The structure reveals a alpha/beta hydrolase fold. Work was performed by Chloé and Sibylle, well done !

Dugelay et al., 2025


https://journals.iucr.org/paper?S2053230X25006697

26 Nov 2025

MMSB Unit retreat in Autrans

We have had the chance to participate to the MMSB unit retreat in the beautiful Autrans in the mountain Vercors (French Alps). 

A lot of fun and great exchanges with all the teams from the unit !

17 Mar 2025

February 17-20. The lab was out at the International T4SS conference in Nancy, France.

Chloé presented here data on the VirJ protein. 

laurent presented a new story on a protein involved in conjugation. 

Alpay and Priscillia  had posters on H. pylori T4SS. 

Lot of work  but great experience

17 Mar 2025

Conference BMSV, CapeTown 2025, february 2-7

Sibylle and Laurent had the chance to participate to the 2025 BMSV conference in Cape Town, South Africa. 

A spectacular venue and Scientific program !

17 Mar 2025

January 2025 we have a new comer !

Chaimaa Chouaib start her Master 2 internship in the lab. She will stay with us 6 months and try to solve the structure of bacterial effectors.

Welcome Chaimaa and good luck !

20 Dec 2024

2024 Christmas lunch at the Altitude restaurant !

26 Nov 2025

The team has contributing to organizing the "Société Française de Biochimie et Biologie Moléculaire" Annual Congress in Lyon !

A lot of work but a massive success for this 2-days event gathering more than 130 students, scientists, professors and sponsors !

Fantastic science on display !

29 Nov 2023

New article from the team

We publish a book chapter describing a pipeline from protein to structure determination and analysis using X-ray crystallography in the beautiful book Methods in Molecular Biology edited by E. Cascales and L. Journet.

Congratulations Chloé  !

Check out the article (Dugelay et al., 2023) here !

13 Nov 2023

BSI conference 2023

We are at the BSI 2023 conference organised in Marseille. Chloé is presenting her poster on her results on Brucella and Laurent is giving a talk on Helicobacter latest developpement

10 Nov 2023
Chloé and Marine carving !

Chloé and Marine carving !

IBCP Pumpkin carving contest Winner

The lab has participated to the IBCP carving contest.

and won the prize ! for the second year

Back to back champion ! well done

10 Nov 2023

The winning photo showing the scene created with the two pumpkins

2 Oct 2023

Alpay Aydin starts his PhD on Helicobacter pylori type IV secretion system. He will be co-supervised by Laurent and Priscillia

Welcome Alpay !

3 Sep 2023

EMBO Workshop Istanbul

Laurent is giving a lecture at the EMBO workshop on Macromolecular Complexes. Great venue and wonderful hospitality

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